Amebiasis Newsletter

Editors: C. G. Clark, LSHTM, London, England, L. S. Diamond, NIH, Bethesda MD, USA,

M. Espinosa Cantellano, A. Martínez-Palomo, CINVESTAV-IPN, México DF

Nº 16, Spring 1998

Correspondence should be sent to:

Dr. C. Graham Clark, Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, England, G.B.

OR: Dra. Martha Espinosa Cantellano, Departamento de Patología Experimental, CINVESTAV-IPN, Aptdo. Postal 14-740, CP 07000 México D.F., México

Entamoeba on the World Wide Web

As announced in the last Newsletter, the 'Entamoeba Homepage', a website for Entamoeba researchers is now available. The site is being visited by about 100 people per week on average, which hopefully indicates that is a useful resource! The content of the site continues to be updated and modified. Future plans include a gallery of portraits of the great researchers in the field of amebiasis, additional research methods, etc. For those who have not yet visited the Entamoeba Homepage it can be found at:

For it to remain useful it is important that the information it contains is as up-to-date as possible. For this reason we request that you check your entry in the directory of addresses. It is especially important that contact information be kept up to date and that we remove individuals from the list when they are no longer in the field. More and more people have access to electronic mail and we frequently find out about such individuals indirectly, not because they write to inform us. Please help us!

As always, all comments and reports of problems will be gratefully received as would additional links to appropriate web pages, graphics files, and any other useful material. You need not know how to prepare web pages in order to contribute to the site. We can easily convert electronic text or word processor files to the correct format for viewing on the web. We look forward to hearing from you!

Recent Publications in Amebiasis

Abaza, H., El Zayadi, A.R., Kabil, S.M. & Rizk, H. (1998) Nitazoxanide in the treatment of patients with intestinal protozoan and helminthic infections: A report on 546 patients in Egypt. Curr. Therapeut. Res. Clin. Exper. 59: 116-121.

Adebajo, A.O. (1996) Rheumatic manifestations of tropical diseases. Curr. Opin. Rheumatol. 8: 85-89.

Aihara, M. (1997) [Infectious disease in Kenya: epidemiological study of diarrhoeal disease in children (in Japanese)]. Japanese J. Clin. Pathol. 45: 421-426.

Akhter, J., Hussain Qadri, S.M. & Kedadah, E. (1997) Serodiagnosis of parasitic infections at a tertiary care centre in Saudi Arabia. Saudi Pharmaceut. J. 5: 176-178.

Alon, R.N., Bracha, R. & Mirelman, D. (1997) Inhibition of expression of the lysine-rich 30kDa surface antigen of Entamoeba dispar by transcription of its antisense RNA. Mol. Biochem. Parasitol. 90: 193-201.

Araj, G.F., Abdul-Baki, N.Y., Hamze, M.M., Alami, S.Y., Nassif, R.E. & Naboulsi, M.S. (1996) Prevalence and etiology of intestinal parasites in Lebanon. Lebanese Med. J. 44: 129-133.

Baez Camargo, M., Gharaibeh, R., Riveron, A.M., Hernández, F.D.L., Luna, J.P., Gariglio, P., Chávez, P. & Orozco, E. (1997) Gene amplification in Entamoeba histolytica. Invasion & Metastasis 16: 269-279.

Baqai, R. (1996) Role of cytokines in parasitic disease. J. Pakistan Med. Assoc. 46: 48-49.

Barcat, D., Constans, J., Jarnier, P., Le Metayer, P., Gosse, P. & Conri, C. (1998) [Thrombosis of the inferior vena caval and right atrium in amoebic abscess of the liver (in French)]. Archives Mal. Coeur Vaiss. 91: 271-273.

Bauder, B., Auer, H. & Aspöck, H. (1997) [Serodiagnosis of infections with Entamoeba histolytica using ELISA and Western blot (in German)]. Mitt. Österr. Ges. Tropenmed. Parasitol. 19: 105-112.

Bernieri, F., Galli, D., Crotti, D. & del Sante, M. (1996) [A multicentre study by the Italian Association of Clinical Microbiology Parasitology Study Committee (AMCLI CoSP) on the distribution of intestinal parasites in Italy: intestinal parasites in immigrants (in Italian)]. G. Italiano Med. Trop. 1: 97-99.

Bhatia, S., Karnad, D.R. & Oak, J.L. (1998) Randomized double-blind trial of metronidazole versus secnidazole in amebic liver abscess. Indian J. Gastroenterol. 17: 53-54.

Bhattacharya, A., Anand, M.T., Paul, J., Yadav, N. & Bhattacharya, S. (1998) Molecular changes in Entamoeba histolytica in response to bacteria. J. Euk. Microbiol. 45: 28S-33S.

Bhattacharya, S., Som, I. & Bhattacharya, A. (1998) The ribosomal DNA plasmids of Entamoeba. Parasitol. Today 14: 181-185.

Blayac, P.M., Maubon, A., Ferru, J.M., Berges, P., Reynaud, D. & Rouanet, J.P. (1997) [Hepatic abscess with hepato-bronchial fistula (in French)]. J. Radiol. 78: 469-471.

Bovornkitti, S. (1996) Tropical pulmonary diseases. Respirology 1: 11-21.

Bruchhaus, I., Richter, S. & Tannich, E. (1998) Recombinant expression and biochemical characterization of an NADPH:flavin oxidoreductase from Entamoeba histolytica. Biochem. J. 330: 1217-1221.

Brunser, O., Espinoza, J. & Brunser, A.M. (1997) Etiology of diarrhea: Bacteria and parasites. Nestle Nutrition Workshop Series 38: 13-37.

Byington, C.L., Dunbrack, R.L., Jr., Whitby, F.G., Cohen, F.E. & Agabian, N. (1997) Entamoeba histolytica: computer-assisted modeling of phosphofructokinase for prediction of broad-spectrum antiparasitic agents. Exp. Parasitol. 87: 194-202.

Calzada, F., Alanis, A.D., Meckes, M., Tapia Contreras, A. & Cedillo Rivera, R. (1998) In vitro susceptibility of Entamoeba histolytica and Giardia lamblia to some medicinal plants used by the people of Southern Mexico. Phytother. Res. 12: 70-72.

Chao, T.H., Li, Y.H., Tsai, L.M., Tsai, W.C., Teng, J.K., Lin, L.J. & Chen, J.H. (1998) Amebic liver abscess complicated with cardiac tamponade and mediastinal abscess. J. Formosan Med. Assoc. 97: 214-216.

Chatterjee, D.K., Iyer, S.N. & Venugopalan, B. (1997) Antiamoebic activity of 3,3'- fluro-4,4'-di-(pyrrolidine-2-ylidene amino)-diphenyl (liroldine), against experimentally infected intestinal and hepatic amoebiasis. Indian J. Exp. Biol. 35: 765-770.

Chen, Z.X. (1996) [Care of amebic hepatic abscess (in Chinese)]. Chung Hua Hu Li Tsa Chih 31: 79-81.

Chigusa, Y., Kirinoki, M., Yokoi, H., Kawai, S., Matsuda, H., Yasuraoka, K., Bugawan, L.E. & Blas, B.L. (1997) A survey of intestinal parasitic infections in San Narciso, Victoria, Oriental Mindoro, Philippines. Japanese J. Trop. Med. Hyg. 25: 7-9.

Connaris, S. & Greenwell, P. (1997) Glycosidases in mucin-dwelling protozoans. Glycoconjugate J. 14: 879-882.

Cook, G.C. (1997) Liver involvement in systemic infection. Eur. J. Gastroenterol. Hepatol. 9: 1239-1247.

Dautov, F.F. (1997) [The diagnosis and surgical treatment of intestinal amebiasis (in Russian)]. Med. Parazit. (Moscow) 4: 8-11.

de Alencar, L.C.A., Magalhaes, V., de Melo, V.M., Aka, I., Magalhaes, M. & Kobayashi, S. (1996) [Absence of invasive amoebiasis in male homosexual AIDS patients in Recife (in Portuguese)]. Rev. Soc. Brasileira Med. Trop. 29: 319-322.

DeLuca, M.M., Pezzani, B.C., Cordoba, M.A. & Basualdo, J.A. (1997) Characterization and quantitation of parasite species in the effluents of the Berisso main sewage channel, Buenos Aires, Argentina. Zbl. Hyg. Umweltmed. 200: 349-357.

Deng, Z., Huang, M., Singh, K., Albach, R.A., Latshaw, S.P., Chang, K.P. & Kemp, R.G. (1998) Cloning and expression of the gene for the active PPi-dependent phosphofructokinase of Entamoeba histolytica. Biochem. J 329: 659-664.

Dodson, J.M., Clark, C.G., Lockhart, L.A., Leo, B.M., Schroeder, J.W. & Mann, B.J. (1997) Comparison of adherence, cytotoxicity, and Gal/GalNAc lectin gene structure in Entamoeba histolytica and Entamoeba dispar. Parasitol. Int. 46: 225-235.

Doumbo, O., Rossignol, J.F., Pichard, E., Traore, H.A., Dembele, M., Diakite, M., Traore, F. & Diallo, D.A. (1997) Nitazoxanide in the treatment of cryptosporidial diarrhea and other intestinal parasitic infections associated with acquired immunodeficiency syndrome in tropical Africa. Am. J. Trop. Med. Hyg. 56: 637-639.

Escandón Romero, C., García Manzo, N.T., Escobedo de la Peña, J., Hernández Ramos, J.M., Olvera Alvarez, J. & Cabral Soto, J. (1996) [Amebiasis and amebic liver abscess in Mexico: a present-day public health problem (in Spanish)]. Rev. Gastroenterol. Mex. 61: 378-386.

Evans, C.A.W., Gilman, R.H., Rabbani, G.H., Salazar, G. & Ali, A. (1997) Gastric acid secretion and enteric infection in Bangladesh. Trans. R. Soc. Trop. Med. Hyg. 91: 681-685.

Franco, E., Vazquez-Prado, J. & Meza, I. (1997) Fibronectin-derived fragments as inducers of adhesion and chemotaxis of Entamoeba histolytica trophozoites. J. Infect. Dis. 176: 1597-1602.

Furnee, C.A., West, C.E., van der Haar, F. & Hautvast, J.G. (1997) Effect of intestinal parasite treatment on the efficacy of oral iodized oil for correcting iodine deficiency in schoolchildren. Am. J. Clin. Nutr. 66: 1422-1427.

Gamboa, M.I., Basualdo Farjat, J.A., Kozubsky, L., Costas, M.E., Cueto Rua, E. & Lahitte, H.B. (1996) [Enteroparasitoses in two periurban populations of La Plata, Argentina (in Spanish)]. Bol. Chileno Parasitol. 51: 37-41.

Gangopadhyay, S.S., Ray, S.S., Kennady, K., Pande, G. & Lohia, A. (1997) Heterogeneity of DNA content and expression of cell cycle genes in axenically growing Entamoeba histolyticaHM1:IMSS clone A. Mol. Biochem. Parasitol. 90: 9-20.

Gardien, E., Schlegel, L., Desbois, N. & Chout, R. (1997) [Prevalence of intestinal parasitism in public laboratories of Martinique: progress from 1988 to 1995 (in French)]. Bull. Soc. Pathol. Exot. 90: 169-171.

Garlicki, A., Kluba-Wojewoda, U., Krukowiecki, J. & Kowalski, P. (1996) [Conservative treatment of hepatic amebic abscesses (in Polish)]. Pol. Tyg. Lek. 51: 233-234.

Gatti, S., Mahdi, R., Bruno, A., Cevini, C. & Scaglia, M. (1998) A survey of amoebic infection in the Wonji area of central Ethiopia. Ann. Trop. Med. Parasitol. 92: 173-179.

Ghose, R. (1998) Sporadic amoebic liver abscess in the North Island (Letter). New Zealand Med. J. 111: 83.

Giacometti, A., Cirioni, O., Balducci, M., Drenaggi, D., Quarta, M., DeFedericis, M., Ruggeri, P., Colapinto, D., Ripani, G. & Scalise, G. (1997) Epidemiologic features of intestinal parasitic infections in Italian mental institutions. Eur. J. Epidemiol. 13: 825-830.

Gilchrist, C.A., Mann, B.J. & Petri, W.A., Jr. (1998) Control of ferredoxin and Gal/GalNAc lectin gene expression in Entamoeba histolytica by a cis-acting DNA sequence. Infect. Immun. 66: 2383-2386.

Gomes, M.A., Melo, M.N., Pesquero, J.L. & Silva, E.F. (1997) Characterization for virulence of an axenic strain of Entamoeba histolytica: evidence for overexpression of two proteins. Arch. Med. Res. 28: 489-492.

Gómez, A., Leyva, O., Martínez, M.d.C., Garduño, G., Ramos, F., Moran, P., Melendro, E.I., Muñoz, O. & Ximénez, C. (1997) Prospective study of Entamoeba dispar infection in a cohort of mothers and their infants: relationship to serum antibody response. Am. J. Trop. Med. Hyg. 57: 530-537.

Gómez, C., Pérez, D.G., López-Bayghen, E. & Orozco, E. (1998) Transcriptional analysis of the EhPgp1 promoter of Entamoeba histolytica multidrug-resistant mutant. J. Biol. Chem. 273: 7277-7284.

Göttke, M.U., Keller, K., Belley, A., Garcia, R.M., Hollingsworth, M.A., Mack, D.R. & Chadee, K. (1998) Functional heterogeneity of colonic adenocarcinoma mucins for inhibition of Entamoeba histolytica adherence to target cells. J. Euk. Microbiol. 45: 17S-23S.

Guo, Z., Wang, Z., An, Y. & Zhu, H. (1996) Application of polymerase chain reaction for diagnosing amebic liver abscess. Chinese Med. Sci. J. 11: 100-102.

Haq, R.U., Qazi, J.I. & Shakoori, A.R. (1998) Growth and survival of protozoa isolated from a tannery effluent. Folia Microbiol. 43: 109-112.

Haque, R., Ali, I.K.M., Akther, S. & Petri, W.A., Jr. (1998) Comparison of PCR, isoenzyme analysis, and antigen detection for diagnosis of Entamoeba histolytica infection. J. Clin. Microbiol. 36: 449-452.

Hokama, S., Toda, T., Kusano, N., Nakamura, H., Nakasone, I., Nagamine, T., Urasaki, H., Chinen, S., Kinjoh, N., Sakiyama, K., Yohena, K., Taira, S., Kyan, T. & Ohshiro, M. (1996) [Recent features of parasites detected from clinical specimens (in Japanese)]. Japanese J. Clin. Pathol. 44: 379-383.

Hommel, M. (1996) [Physiopathology of protozoan infections (in French)]. C. R. Seances Soc. Biol. Fil. 190: 341-355.

Honein, K. & Yaghi, C. (1996) [Multiple amebic liver abscess (in French)]. J. Med. Liban 44: 44-47.

Ighogboja, I.S. & Ikeh, E.I. (1997) Parasitic agents in childhood diarrhoea and malnutrition. West Afr. J. Med. 16: 36-39.

Isik, K. (1996) [The investigation of intestinal parasites in Izmir, Karsiyaka-Menemen-Aliaga (in Turkish)]. Turkiye Parazitoloji Dergisi 20: 401-405.

Jackson, T.F.H.G. (1998) Entamoeba histolytica and Entamoeba dispar are distinct species; clinical, epidemiological and serological evidence. Int. J. Parasitol. 28: 181-186.

Jacobs, T., Bruchhaus, I., Dandekar, T., Tannich, E. & Leippe, M. (1998) Isolation and molecular characterization of a surface-bound proteinase of Entamoeba histolytica. Mol. Microbiol. 27: 269-276.

Johansen, J. & Sindet Pedersen, S. (1998) Entamoeba infected orbital cysts as a late complication to orbital floor fractures. Acta Opthalm. Scand. 76: 123-124.

Kabatereine, N.B., Kemijumbi, J., Kazibwe, F. & Onapa, A.W. (1997) Human intestinal parasites in primary school children in Kampala, Uganda. East Afr. Med. J. 74: 311-314.

Kang, G., Mathew, M.S., Rajan, D.P., Daniel, J.D., Mathan, M.M., Mathan, V.I. & Muliyil, J.P. (1998) Prevalence of intestinal parasites in rural Southern Indians. Trop. Med. Int. Hlth. 3: 70-75.

Kasim, H., Ay, Y.D., Oguz, M.C., Ozturk, M.O. & Coskun, S.Z. (1996) [The prevalence of gastro-intestinal parasites in primary school children in the Bursa region (in Turkish)]. Turkiye Parazitoloji Dergisi 20: 191-197.

Kim, J.M., Jung, H.C., Im, K.I., Cho, Y.J., Song, I.S. & Kim, C.Y. (1996) Study for interaction between Escherichia coli and Entamoeba histolytica in induction of cytokine gene expression in human colon epithelial cells. J. Korean Soc. Microbiol. 31: 135-144.

Kobayashi, S., Imai, E., Tachibana, H., Fujiwara, T. & Takeuchi, T. (1998) Entamoeba dispar: cultivation with sterilized Crithidia fasciculata. J. Euk. Microbiol. 45: 3S-8S.

Kretschmer, R. & López-Osuna, M. (1997) Eosinophils, HLA and amebic disease (Editorial). Infection 25: 327-328.

Kuzna-Grygiel, W. (1996) [Cytochemical study on the activity of enzymes in trophozoites of Entamoeba histolytica from the cecum of guinea pigs with invasive and non-invasive amebiasis (in Polish)]. Wiad. Parazytol. 42: 407-414.

Leipe, D.D. (1997) Morphological and molecular data in protozoan systematics. Verh. Deutsch. Zool. Gesell. 89: 63-69.

Lo, C.T. & Lee, K.M. (1996) Intestinal parasites among the Southeast Asian laborers in Taiwan during 1993-1994. Chinese Med. J. 57: 401-404.

López-Osuna, M., Velázquez, J.R. & Kretschmer, R.R. (1997) Does the eosinophil have a protective role in amebiasis? Mem. Inst. Osw. Cruz 92: 237-240.

Machado, M.C.C. & Herman, P. (1997) Amebic liver abscess. In R. V. Cohen, F. Aun and D. E. Uip (Eds.), Tropical Surgery. Basel: Karger, pp. 213-218.

Mai, Z. & Samuelson, J. (1998) A new gene family (ariel) encodes asparagine-rich Entamoeba histolytica antigens, which resemble the amebic vaccine candidate serine-rich E. histolytica protein. Infect. Immun. 66: 353-355.

Makioka, A., Ohtomo, H., Kobayashi, S. & Takeuchi, T. (1997) Comparison of DNA polymerase between Entamoeba histolytica and E. dispar. Parasitol. Int. 46: 27-30.

Maksoud Filho, J.G. & Rocha, R.F.C.d. (1997) Toxic colitis due to amebiasis in children. In R. V. Cohen, F. Aun and D. E. Uip (Eds.), Tropical Surgery. Basel: Karger, pp. 119-124.

Mann, B.J. & Lockhart, L.A. (1998) Molecular analysis of the Gal/GalNAc adhesin of Entamoeba histolytica. J. Euk. Microbiol. 45: 13S-16S.

Mansour, N.S., Youssef, F.G., Mikhail, E.M. & Mohareb, E.W. (1997) Amebiasis in schistosomiasis endemic and non-endemic areas of Egypt. J. Egypt. Soc. Parasitol. 27: 617-628.

Martínez-Palomo, A. & Espinosa-Cantellano, M. (1998) Amoebiasis: new understanding and new goals. Parasitol. Today 14: 1-3.

McGonigle, S., Dalton, J.P. & James, E.R. (1998) Peroxidoxins: A new antioxidant family. Parasitol. Today 14: 139-145.

Mehlotra, R.K. (1998) Differentiation of pathogenic and non-pathogenic Entamoeba: has the question been answered? Indian J Gastroenterol 17: 58-60.

Mercado, R., Otto, J.P., Musleh, M. & Perez, M. (1997) [Human infection by intestinal protozoa and helminths in Calbuco County, X Region, Chile, 1997 (in Spanish)]. Bol. Chileno Parasitol. 52: 36-38.

Moazam, F. & Nazir, Z. (1998) Amebic liver abscess: Spare the knife but save the child. J. Pediatr. Surg. 33: 119-122.

Molyneux, D.H. (1997) The protozoan view of the human condition. Postgrad. Med. J. 73: 769-770.

Moody, S., Becker, S., Nuchamowitz, Y. & Mirelman, D. (1998) Identification of significant variation in the composition of lipophosphoglycan-like molecules of E. histolytica and E. dispar. J. Euk. Microbiol. 45: S9-S12.

Moshitch-Moshkovitch, S., Petter, R., Levitan, A., Stolarsky, T. & Mirelman, D. (1998) Regulation of expression of ribosomal protein L-21 genes of Entamoeba histolytica and E. dispar is at the post-transcriptional level. Mol. Microbiol. 27: 677-686.

Motta, C.M.S., Beltrão, E.I.C., Amorim, R.V.S. & Carvalho, L.B., Jr. (1997) Entamoeba histolytica and Entamoeba dispar in the Northeast Brazil. Rev. Inst. Med. Trop. São Paulo 39: 365-366.

Mounadif, M., Badre, W., Bellabah, A., Jamil, D., Alaoui, R. & Cherkaoui, A. (1997) [Amebic abscess of the spleen. Two case reports with a review of the literature (in French)]. Semaine des Hôpitaux 73: 875-878.

Mukhopadhyay, C. & Lohia, A. (1998) Modeling of Entamoeba histolytica ferredoxin. J. Biomol. Struct. Dyn. 15: 663-672.

Myjak, P., Kur, J. & Pietkiewicz, H. (1997) Usefulness of new DNA extraction procedure for PCR technique in species identification of Entamoeba isolates. Wiad. Parazytol. 43: 163-170.

Nikolic, A., Durkovic-Dakovic, O., Bobic, B. & Vukovic, D. (1996) Intestinal parasitism in schoolchildren in Serbia. Significance of rural vs. urban environment. Arch. Gastroenterohepatol. 15: 89-91.

Niscigorska, J. & Boron-Kaczmarska, A. (1996) [Amebic liver abscess: personal observations (in Polish)]. Przegl. Epidemiol. 50: 281-286.

Offiong, O.E., Etok, C. & Martelli, S. (1996) Synthesis and biological activity of platinum group metal complexes of o-vanillin thiosemicarbazones. Farmaco 51: 801-808.

Ohnishi, K. & Murata, M. (1997) Present characteristics of symptomatic amebiasis due to Entamoeba histolytica in the east-southeast area of Tokyo. Epidemiol. Infect. 119: 363-367.

Okoronkwo, M.O. & Zoakah, A.I. (1997) Gastrointestinal parasitic infection in a drought afflicted community in northern Nigeria. Nig. Qt. J. Hosp. Med. 7: 379-383.

Olaeta Elizalde, R., Perez Huacuja, R. & Najera Ruano, S. (1996) [Comparison of quinfamide vs etofamide in the Mexican population with intestinal amebiasis (in Spanish)]. Acta Gastroenterol. Latinoamer. 26: 277-280.

Olmos, M., Molina, C., Piskorz, E., Tawil, J., Magnanini, F., Casiro, A., Cahn, P., Concetti, H., Janeiro, M., Guelfand, L. & Kaufman, S. (1996) [Diarrhea and AIDS: more complex diagnostic techniques, better therapeutic results (in Spanish)]. Acta Gastroenterol. Latinoamer. 26: 91-100.

Ono, K., Uga, S., Sawada, Y., Shimada, K., Horikoshi, T., Kusuda, H. & Matsumura, T. (1996) [Comparative study on serological diagnosis of entamoebiasis histolytica (in Japanese)]. Japanese J. Clin. Pathol. 44: 362-366.

Ortner, S., Binder, M., Scheiner, O., Wiedermann, G. & Duchêne, M. (1997) Molecular and biochemical characterization of phosphoglucomutases from Entamoeba histolytica and Entamoeba dispar. Mol. Biochem. Parasitol. 90: 121-129.

Owen, R.L. (1997) Parasitic diseases. In M. Feldman, B. F. Scharschmidt and M. H. Sleisinger (Eds.), Gastrointestinal and Liver Disease. Philadelphia, PA: W.B. Saunders, pp. 1648-1679.

Paredes, A., Ibar, M., Echeverria, X., Toledo, M.I. & Corquera, W. (1996) [Intestinal protozoal and helminth infections in a rural school with environmental health problems in the municipality of Vilcun, IX Region, Chile (in Spanish)]. Parasitol. al Dia 20: 70-73.

Paugam, A., Tourte Schaefer, C. & Dupouy Camet, J. (1998) [Entamoeba histolytica and Entamoeba dispar: two morphologically identical amebas of which only the first is pathogenic. Practical implications and perspectives (in French)]. Semaine des Hôpitaux 74: 177-181.

Perea, R., Bassas, E., Lepe, J.A., Lombardo, M. & Garces, M. (1998) [The prevalence of antibodies to Entamoeba histolytica in the northern area of the province of Huelva (Spain) (in Spanish; Letter)]. Medicina Clínica 110: 275.

Pérez Armengol, C., Ariza Astolfi, C., Ubeda Ontiveros, J.M., Guevara Benitez, D.C., de Rojas Alvarez, M. & Lozano Serrano, C. (1997) [Epidemiology of children's intestinal parasitism in the Guadalquivir Valley, Spain (in Spanish)]. Rev. Esp. Salud Publica 71: 547-552.

Pérez, D.G., Gómez, C., López-Bayghen, E., Tannich, E. & Orozco, E. (1998) Transcriptional analysis of the EhPgp5 promoter of Entamoeba histolytica multidrug-resistant mutant. J. Biol. Chem. 273: 7285-7292.

Pérez, E., Muñoz, M.D. & Ortega, A. (1998) Entamoeba histolytica: Collagen-induced AP-1 DNA binding activity. FEMS Microbiol. Letts. 159: 187-192.

Pollok, R.C.G. & Farthing, M.J.G. (1997) Intestinal parasites. Curr. Opinion Infect. Dis. 10: 414-418.

Presber, H.-W. (1997) [Domestic intestinal parasites (in German)]. Z. Allgemeinmed. 73: 1225-1233.

Puente, D.S., Subirats, M., Cobo, J. & Babe, J. (1998) [Image of the week - Amebic hepatic abscess (in Spanish)]. Medicina Clinica 110: 40.

Rajak, C.L., Gupta, S., Jain, S., Chawla, Y., Gulati, M. & Suri, S. (1998) Percutaneous treatment of liver abscesses: needle aspiration versus catheter drainage. Am. J. Roentgenol. 170: 1035-1039.

Ralls, P.W. (1998) Focal inflammatory disease of the liver. Radiol. Clin. North Am. 36: 377-389.

Ram, S., Khurana, S., Kaushal, V. & Khurana, S.B. (1997) Infectious diarrhoea: an update. Indian J. Med. Sci 51: 196-203.

Ray, S.S., Gangopadhyay, S.S., Pande, G., Samuelson, J. & Lohia, A. (1997) Primary structure of Entamoeba histolytica -tubulin and localisation of amoebic microtubule organising centres. Mol. Biochem. Parasitol. 90: 331-336.

Rivero de R., Z., Acevedo, C., Casanova, I., Hernandez, S. & Malaspina, A. (1996) [Enteroparasitoses in school children from two rural school units in La Canada Municipality, Zulia State, Venezuela (in Spanish)]. Kasmera 24: 151-177.

Robert, R. (1997) [Rapid tests for diagnosis of parasitic and fungal diseases (in French)]. Immuno-Analyse et Biologie Specialisée 12: 232-240.

Roger, A.J., Svärd, S.G., Tovar, J., Clark, C.G., Smith, M.W., Gillin, F.D. & Sogin, M.L. (1998) A mitochondrial-like chaperonin 60 gene in Giardia lamblia: Evidence that diplomonads once harbored an endosymbiont related to the progenitor of mitochondria. Proc. Natl. Acad. Sci. USA 95: 229-234.

Romero Cabello, R., Robert Guerrero, L., Muñoz García, R. & Geyne Cruz, A. (1997) Nitazoxanide for the treatment of intestinal protozoan and helminthic infections in Mexico. Trans. R. Soc. Trop. Med. Hyg. 91: 701-703.

Romero, R., Robert, L., Muñoz, R., Alarcón, A., Tay, J. & Sánchez, J.T. (1997) [Prophylactic treatment with quinfamide for the community control of intestinal infection with Entamoeba histolytica (in Spanish)]. Parasitol. al Dia 21: 97-103.

Rudrapatna, J.S., Kumar, V. & Sridhar, H. (1997) Intestinal parasitic infections in patients with malignancy. J. Diarrh. Dis. Res. 15: 71-74.

Saavedra-Lira, E., Ramírez-Silva, L. & Pérez-Montfort, R. (1998) Expression and characterization of recombinant pyruvate phosphate dikinase from Entamoeba histolytica. Biochim. Biophys. Acta 1382: 47-54.

Sahara, K., Hori, W., Masuda, T., Ohata, K., Yamazaki, F., Akahane, S., Hattori, H., Yuasa, H., Hashizume, I., Tanaka, Y., Nagakura, K. & Tachibana, H. (1996) [Invasive amebiasis at an institution for the mentally retarded in Shizuoka Prefecture (in Japanese)]. Kansenshogaku Zasshi 70: 1-6.

Samarawickrema, N.A., Brown, D.M., Upcroft, J.A., Thammapalerd, N. & Upcroft, P. (1997) Involvement of superoxide dismutase and pyruvate:ferredoxin oxidoreductase in mechanisms of metronidazole resistance in Entamoeba histolytica. J. Antimicrob. Chemother. 40: 833-840.

Sánchez, L.B. & Müller, M. (1998) Cloning and heterologous expression of Entamoeba histolytica adenylate kinase and uridylate/cytidylate kinase. Gene 209: 219-228.

Sarda, A.K., Kannan, R., Gupta, A., Mahajan, V., Jain, P.K. & Prasad, S. (1998) Amebic liver abscess with jaundice. Surgery Today (Japanese J. Surg.) 28: 305-307.

Seto, S. & Yano, K. (1996) [Protozoal pericarditis (in Japanese)]. Ryoikibetsu Shokogun Shirizu 1996(13): 508-10.

Sharma, M.P., Dasarathy, S., Sushma, S. & Verma, N. (1995) Long term follow-up of amebic liver abscess: clinical and ultrasound patterns of resolution. Trop. Gastroenterol. 16: 24-28.

Sharma, V., Thakur, T.S., Thakur, S.S. & Goyal, A. (1996) Clinical significance of immunoglobulin alterations in amoebiasis (Letter). Indian. J. Pathol. Microbiol. 39: 251.

Sharma, M.P. & Dasarathy, S. (1997) Invasive amoebiasis: pathogenic factors and clinical relevance. Gastroenterol. Today 3: 155-161.

Shibayama, M., Campos-Rodríguez, R., Ramírez-Rosales, A., Flores-Romo, L., Espinosa-Cantellano, M., Martínez-Palomo, A. & Tsutsumi, V. (1998) Entamoeba histolytica: liver invasion and abscess production by intraperitoneal inoculation of trophozoites in hamsters, Mesocricetus auratus. Exp. Parasitol. 88: 20-27.

Simon, F. & Almeras, D. (1997) [Metronidazole (Flagyl) (in French)]. Méd. Trop. 57: 136.

Singh, R. & Vyas, S.P. (1997) Development and characterization of a mini capsular extrusion system for enteric delivery of metronidazole bearing liposomes. J. Drug Targeting 4: 265-270.

Sopina, V.A. (1997) [The cell biology of amebas and ameba-flagellates: parasites of man and animals (in Russian)]. Tsitologiia 39: 361-386.

Spice, W.M. & Ackers, J.P. (1998) The effects of Entamoeba histolytica lysates on human colonic mucins. J. Euk. Microbiol. 45: 24S-27S.

Sultan, F., Jin, L.L., Jobling, M.G., Holmes, R.K. & Stanley, S.L., Jr. (1998) Mucosal immunogenicity of a holotoxin-like molecule containing the serine-rich Entamoeba histolytica protein (SREHP) fused to the A2 domain of cholera toxin. Infect. Immun. 66: 462-468.

Suwatano, O. (1997) Acute diarrhea in under five-year-old children admitted to King Mongkut Prachomklao Hospital, Phetchaburi province. J. Med. Assoc. Thailand 80: 26-33.

Takahashi, T., Gamboa-Domínguez, A., Gómez-Mendez, T.J., Remes, J.M., Rembis, V., Martínez-González, D., Gutiérrez-Saldivar, J., Morales, J.C., Granados, J. & Sierra-Madero, J. (1997) Fulminant amebic colitis: analysis of 55 cases. Dis. Colon Rectum 40: 1362-1367.

Tandon, A., Jain, A.K., Dixit, V.K., Agarwal, A.K. & Gupta, J.P. (1997) Needle aspiration in large amoebic liver abscess. Trop. Gastroenterol. 18: 19-21.

Tasci, S. & Balcioglu, I.C. (1996) [Distribution of intestinal parasites diagnosed in Manisa Celal Bayar University Medical Faculty Health Application and Research Centre in 1995 (in Turkish)]. Turkiye Parazitoloji Dergisi 20: 387-393.

Torres, P., Otth, L., Montefusco, A., Wilson, G., Ramirez, C., Acuna, M. & Marin, F. (1997) [Infection by intestinal protozoa and helminths in schoolchildren from riverside sectors, with different fecal contamination levels, of Valdivia river, Chile (in Spanish)]. Bol. Chileno Parasitol. 52: 3-11.

Tran, V.Q., Herdman, D.S., Torian, B.E. & Reed, S.L. (1998) The neutral cysteine proteinase of Entamoeba histolytica degrades IgG and prevents its binding. J. Infect. Dis. 177: 508-511.

Uga, S., Ono, K., Kataoka, N. & Hasan, H. (1996) Seroepidemiology of five major zoonotic parasite infections in inhabitants of Sidoarjo, East Java, Indonesia. S.E. Asian J. Trop Med. Publ. Hlth. 27: 556-561.

Urbani, C., Touré, A., Hamed, A.O., Albonico, M., Kane, I., Cheikna, D., Hamed, N.O., Montresor, A. & Savioli, L. (1997) [Intestinal parasitic infection and schistosomiasis in the Senegal River valley of the Islamic Republic of Mauritania (in French)]. Méd. Trop. 57: 157-160.

Vargas-Villarreal, J., Olvera-Rodríguez, A., Mata-Cárdenas, B.D., Martínez-Rodríguez, H.G., Said-Fernández, S. & Alagón-Cano, A. (1998) Isolation of an Entamoeba histolytica intracellular alkaline phospholipase A2. Parasitol. Res. 84: 310-314.

Variyam, E.P. (1998) Intestinal parasitic infections. Curr. Opin. Gastroenterol. 14: 50-56.

Villagómez-Castro, J.C., Calvo-Méndez, C., Vargas-Rodríguez, L., Flores-Carreón, A. & López-Romero, E. (1998) Entamoeba histolytica: solubilization and biochemical characterization of dolichol phosphate mannose synthase, an essential enzyme in glycoprotein biosynthesis. Exp. Parasitol. 88: 111-120.

Wagner, N., Brocker, E.-B. & Klein, C.E. (1997) [Amebasis - a rare differential diagnosis of perianal ulcers (in German)]. Aktuelle Dermatologie 23: 181-183.

Wang, L., Calderon, J. & Stanley, S.L., Jr. (1997) Identification of B cell epitopes in the serine-rich Entamoeba histolytica protein. Am. J. Trop. Med. Hyg. 57: 723-726.

Yereli, K., Girginkardesler, N., Degerli, K. & Ozbilgin, A. (1996) [The lungs and parasitic diseases (in Turkish)]. Turkiye Parazitoloji Dergisi 20: 495-503.

Zdero, M., Cabrera, G., Ponce de Leon, P., Nocito, I. & Echenique, C. (1997) [Parasitosis in an adult population with chronic gastrointestinal disorders (in Spanish)]. Acta Gastroenterol. Latinoam. 27: 67-73.